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Complete information for yap1 gene (protein coding), yes1 associated transcriptional regulator, including Aberrant expression of this gene in adult tissues is associated with tumorigenesis. Function, proteins, disorders, pathways, orthologs, and expression.
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Mutations in this gene cause gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. This gene encodes a transcription factor containing a pou homeodomain that plays a key role in embryonic development and stem cell pluripotency This gene encodes a protein belonging to the raf family of serine/threonine protein kinases
This protein plays a role in regulating the map kinase/erk signaling pathway, which affects cell division, differentiation, and secretion.
The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin.
